VERSE: a novel approach to detect virus integration in host genomes through reference genome customization

Wang et al, Genome Medicine (2015)

Ino de Bruijn / @inodb

VirusFinder 1.0 (2013)

Virus Finder pipeline

VERSE (2015)

VERSE pipeline

Results

Host genome customization

ICORN
Sample 26T from WGS HCC

Virus integration site detection

Data type Known integration sites VERSE VirusFinder VirusSeq
WGS 20 16 13 -
RNA-seq 11 9 8 7
TS 3 3 2 3
Total 34 28 (82%) 23 (68%) -

Questions?

Presentation at
bit.ly/inotalks